Severe thrombocytopenia and hemorrhagic diathesis due to brucellosis.

Role of platelet transfusion in dengue hemorrhagic fever.

Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) are life threatening clinical manifestations of infection due to dengue virus. The clinical features of DHF/DSS are due to bleeding diathesis and increased capillary leak(l). The mechanisms of hemorrhagic manifestations in DHF/DSS are not well understood. The suggested factors contributing to bleeding include thrombocytopenia, coagu...

Brucella-induced Thrombocytopenia and Bleeding

Mild anemia and leukopenia are the most common hematologic problems of acute brucellosis. Mild thrombocytopenia also occurs, but severe cases are uncommon. Thrombocytopenia occurs because of bone marrow suppression, hypersplenisem, hemophagocytosis, and immunologic destruction of the cells or disseminated intravascular coagulation. In endemic areas, hemorrhagic fevers, hematologic malignancies,...

Large Ovarian Hemorrhagic Cyst and Immune Thrombocytopenia as Early Manifestations of Systemic Lupus Erythematosus (SLE)

Hematologic abnormali"es are generally present among systemic lupus erythematosus pa"ents. Idiopathic thrombocytopenic purpura can be the first manifesta"on of SLE, followed by other symptoms and signs of disease appearing several years later. Although bleeding due to immune thrombocytopenic purpura is usually mild and occurs in mucocutaneous surfaces, but it may be severe and represent in u...

Recurrent Epistaxis and Bleeding as the Initial Manifestation of Brucellosis.

Severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. Brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. Bone marrow aspiration (BMA) is mandatory to differentiate from other blood diseases. An 8-year-old boy was admitted with recurrent epistaxis, pe...

Radiation-induced Hemorrhagic Diathesis in Dogs Unassociated with Thrombocytopenia: Association with an Intravascular Protein-polysaccharide Particle.